Changes in coping, pain, and activity after cognitive-behavioral training: a randomized clinical trial for pediatric sickle cell disease using smartphones.

Journal Article (Journal Article)


We examined the outcomes of a cognitive-behavioral therapy (CBT) intervention for pain in pediatric sickle cell disease (SCD) using smartphones as a novel delivery method.

Materials and methods

Forty-six children with SCD received CBT coping skills training using a randomized, waitlist control design. The intervention involved a single session of CBT training and home-based practice using smartphones for 8 weeks. Pre-post questionnaires between the randomized groups were used to evaluate changes in active psychological coping and negative thinking using the Coping Strategies Questionnaire. Daily diaries completed by the full sample during the treatment period were used to assess whether CBT skill use was related to reductions in next-day pain intensity and increases in same-day functional activity.


The pre-post group comparison suggested that the youth increased active psychological coping attempts with the intervention. Daily diary data indicated that when children used CBT skills on days with higher pain, there were reductions in next-day pain intensity. There was no such association between skill use and functional activity.


CBT coping skills training supported using smartphones can increase coping and reduce pain intensity for children with SCD; however, additions to the study protocols are recommended in future studies. Advantages and caveats of using smartphones are also discussed.

Full Text

Duke Authors

Cited Authors

  • Schatz, J; Schlenz, AM; McClellan, CB; Puffer, ES; Hardy, S; Pfeiffer, M; Roberts, CW

Published Date

  • June 2015

Published In

Volume / Issue

  • 31 / 6

Start / End Page

  • 536 - 547

PubMed ID

  • 25503599

Pubmed Central ID

  • PMC4424076

Electronic International Standard Serial Number (EISSN)

  • 1536-5409

International Standard Serial Number (ISSN)

  • 0749-8047

Digital Object Identifier (DOI)

  • 10.1097/ajp.0000000000000183


  • eng