Association between somatic growth trajectory and cognitive functioning in young children with sickle cell disease.
Journal Article
Children with sickle cell disease are at risk of cognitive deficits and somatic growth delays beginning in early childhood. We examined growth velocity from age 2 years (height and body mass index progression over time) and cognitive functioning in 46 children with sickle cell disease 4 to 8 years of age. Height-for-age velocity was not associated with cognitive outcomes. Higher body mass index velocity was associated with higher scores on global cognitive and visual-motor abilities but not processing resources or academic achievement. Body mass index progression over time may be a clinically useful indicator of neurocognitive risk in sickle cell disease, as it may reflect multiple sickle cell disease-related risk factors.
Full Text
Duke Authors
Cited Authors
- Puffer, ES; Schatz, JC; Roberts, CW
Published Date
- August 2016
Published In
Volume / Issue
- 21 / 8
Start / End Page
- 1620 - 1629
PubMed ID
- 25488939
Pubmed Central ID
- 25488939
Electronic International Standard Serial Number (EISSN)
- 1461-7277
International Standard Serial Number (ISSN)
- 1359-1053
Digital Object Identifier (DOI)
- 10.1177/1359105314559861
Language
- eng