Diagnostic tools for monitoring kidney transplant recipients.
Recent advancements in immunobiology have introduced several new diagnostic tools for monitoring kidney transplant recipients. These have been added to more established tests that, although imperfect, remain important benchmarks of diagnostic utility. Both new and old tests can be characterized with regard to their practicality, and as to whether they detect aberrant function or define the cause of dysfunction. Unfortunately, no current test is both practical and specific to a particular disease entity. Accordingly, the diagnosis of graft dysfunction remains dependent on the proper use and interpretation of many studies. This article reviews the current assays that have been evaluated in the clinic for the diagnosis of renal allograft-related diseases. These are limited to assays based on routinely obtainable samples such as blood, biopsy tissue, and urine. Newer studies are presented, along with more mundane assays, to highlight the practical use of studies regardless of their degree of mechanistic sophistication.
Duke Scholars
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Related Subject Headings
- Urology & Nephrology
- Postoperative Period
- Monitoring, Physiologic
- Kidney Transplantation
- Humans
- Graft Rejection
- Diagnostic Techniques and Procedures
- 3202 Clinical sciences
- 1103 Clinical Sciences
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Urology & Nephrology
- Postoperative Period
- Monitoring, Physiologic
- Kidney Transplantation
- Humans
- Graft Rejection
- Diagnostic Techniques and Procedures
- 3202 Clinical sciences
- 1103 Clinical Sciences