Strategies for tolerance induction in nonhuman primates.
Publication
, Journal Article
Hamawy, MM; Knechtle, SJ
Published in: Curr Opin Immunol
October 1998
Organ transplants in nonhuman primates provide a model which closely simulates the biological conditions of human organ transplantation, due to similarities between human and primate MHC (class I and II) structure and expression. Several strategies for tolerance induction have been developed in nonhuman primate models. These include targeting the T cell receptor or costimulatory molecules and the generation of mixed chimerism. Tolerance can be reliably induced in several such models, although none with 100% success.
Duke Scholars
Published In
Curr Opin Immunol
DOI
ISSN
0952-7915
Publication Date
October 1998
Volume
10
Issue
5
Start / End Page
513 / 517
Location
England
Related Subject Headings
- Immunotoxins
- Immunosuppression Therapy
- Immunology
- Humans
- Haplorhini
- Graft Survival
- Chimera
- Bone Marrow Transplantation
- Animals
- 3204 Immunology
Citation
APA
Chicago
ICMJE
MLA
NLM
Hamawy, M. M., & Knechtle, S. J. (1998). Strategies for tolerance induction in nonhuman primates. Curr Opin Immunol, 10(5), 513–517. https://doi.org/10.1016/s0952-7915(98)80216-1
Hamawy, M. M., and S. J. Knechtle. “Strategies for tolerance induction in nonhuman primates.” Curr Opin Immunol 10, no. 5 (October 1998): 513–17. https://doi.org/10.1016/s0952-7915(98)80216-1.
Hamawy MM, Knechtle SJ. Strategies for tolerance induction in nonhuman primates. Curr Opin Immunol. 1998 Oct;10(5):513–7.
Hamawy, M. M., and S. J. Knechtle. “Strategies for tolerance induction in nonhuman primates.” Curr Opin Immunol, vol. 10, no. 5, Oct. 1998, pp. 513–17. Pubmed, doi:10.1016/s0952-7915(98)80216-1.
Hamawy MM, Knechtle SJ. Strategies for tolerance induction in nonhuman primates. Curr Opin Immunol. 1998 Oct;10(5):513–517.
Published In
Curr Opin Immunol
DOI
ISSN
0952-7915
Publication Date
October 1998
Volume
10
Issue
5
Start / End Page
513 / 517
Location
England
Related Subject Headings
- Immunotoxins
- Immunosuppression Therapy
- Immunology
- Humans
- Haplorhini
- Graft Survival
- Chimera
- Bone Marrow Transplantation
- Animals
- 3204 Immunology