Living-unrelated renal donor transplantation: the UNOS experience, 1987-1991. United Network for Organ Sharing.
1. LURD transplants were associated with excellent one-year graft survival of 92%. This survival was superior to that for cadaver transplants performed during the same period. 2. High-risk groups for LURDs are children (age < 18 years) and repeat transplant recipients. Both groups were associated with significantly decreased graft survival. 3. The effects of HLA matching and donor-specific transfusions are not significant. 4. Because of the critical shortage of donor organs and the increasing waiting time for renal transplantation, the use of LURDs can be recommended as a means to expand the number of available organs.
Geffner, SR; D'Alessandro, AM; Kalayoglu, M; Knechtle, SJ; Pirsch, JD; Belzer, FO; Sollinger, HW
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