Handbook on Immunosenescence: Basic Understanding and Clinical Applications
Mathematical modeling of immunosenescence: Scenarios, processes and limitations
Publication
, Chapter
Romanyukha, AA; Rudnev, SG; Sannikova, TA; Yashin, AI
January 1, 2009
Mathematical modeling of immunosenescence is the new area of research emerging at the interface of the immunology, gerontology, and mathematics. In this paper we outline basic variables important for modeling aging immunity. We discuss the role of evolution in shaping pattern of aging in the immune system of modern humans. We investigate mathematical models of postnatal changes in the population of peripheral T-cells, effects of the antigenic load during development on the body growth, and contribution of immunosenescence to the old age increase in the risk of death from respiratory infections.
Duke Scholars
DOI
ISBN
9781402090622
Publication Date
January 1, 2009
Volume
9781402090639
Start / End Page
145 / 163
Citation
APA
Chicago
ICMJE
MLA
NLM
Romanyukha, A. A., Rudnev, S. G., Sannikova, T. A., & Yashin, A. I. (2009). Mathematical modeling of immunosenescence: Scenarios, processes and limitations. In Handbook on Immunosenescence: Basic Understanding and Clinical Applications (Vol. 9781402090639, pp. 145–163). https://doi.org/10.1007/978-1-4020-9063-9_8
Romanyukha, A. A., S. G. Rudnev, T. A. Sannikova, and A. I. Yashin. “Mathematical modeling of immunosenescence: Scenarios, processes and limitations.” In Handbook on Immunosenescence: Basic Understanding and Clinical Applications, 9781402090639:145–63, 2009. https://doi.org/10.1007/978-1-4020-9063-9_8.
Romanyukha AA, Rudnev SG, Sannikova TA, Yashin AI. Mathematical modeling of immunosenescence: Scenarios, processes and limitations. In: Handbook on Immunosenescence: Basic Understanding and Clinical Applications. 2009. p. 145–63.
Romanyukha, A. A., et al. “Mathematical modeling of immunosenescence: Scenarios, processes and limitations.” Handbook on Immunosenescence: Basic Understanding and Clinical Applications, vol. 9781402090639, 2009, pp. 145–63. Scopus, doi:10.1007/978-1-4020-9063-9_8.
Romanyukha AA, Rudnev SG, Sannikova TA, Yashin AI. Mathematical modeling of immunosenescence: Scenarios, processes and limitations. Handbook on Immunosenescence: Basic Understanding and Clinical Applications. 2009. p. 145–163.
DOI
ISBN
9781402090622
Publication Date
January 1, 2009
Volume
9781402090639
Start / End Page
145 / 163