Novel agents or strategies for immunosuppression after renal transplantation


Journal Article (Review)

There have been several recent advances in the use of immunosuppression after organ transplantation. The main goal is to induce transplantation tolerance without immunosuppressive drug toxicity. We reviewed both experimental and clinical organ transplantation studies such as costimulatory blockade agents, sphingosine 1-phosphate receptor analogs, lymphocyte depletion strategies, and chemokine blockade agents in the context of renal transplantation. The newer and safer immunosuppression protocols might provide significant benefit to organ transplant recipients as alternatives to conventional immunosuppressive therapy. © 2003 Lippincott Williams & Wilkins.

Full Text

Duke Authors

Cited Authors

  • Kanmaz, T; Knechtle, SJ

Published Date

  • January 1, 2003

Published In

Volume / Issue

  • 8 / 2

Start / End Page

  • 172 - 178

Electronic International Standard Serial Number (EISSN)

  • 1531-7013

International Standard Serial Number (ISSN)

  • 1087-2418

Digital Object Identifier (DOI)

  • 10.1097/00075200-200306000-00008

Citation Source

  • Scopus