Plasmonic gold nanostars for multi-modality sensing and diagnostics.

Journal Article (Review;Journal Article)

Gold nanostars (AuNSs) are unique systems that can provide a novel multifunctional nanoplatform for molecular sensing and diagnostics. The plasmonic absorption band of AuNSs can be tuned to the near infrared spectral range, often referred to as the "tissue optical window", where light exhibits minimal absorption and deep penetration in tissue. AuNSs have been applied for detecting disease biomarkers and for biomedical imaging using multi-modality methods including surface-enhanced Raman scattering (SERS), two-photon photoluminescence (TPL), magnetic resonance imaging (MRI), positron emission tomography (PET), and X-ray computer tomography (CT) imaging. In this paper, we provide an overview of the recent development of plasmonic AuNSs in our laboratory for biomedical applications and highlight their potential for future translational medicine as a multifunctional nanoplatform.

Full Text

Duke Authors

Cited Authors

  • Liu, Y; Yuan, H; Kersey, FR; Register, JK; Parrott, MC; Vo-Dinh, T

Published Date

  • February 2015

Published In

Volume / Issue

  • 15 / 2

Start / End Page

  • 3706 - 3720

PubMed ID

  • 25664431

Pubmed Central ID

  • PMC4367381

Electronic International Standard Serial Number (EISSN)

  • 1424-8220

International Standard Serial Number (ISSN)

  • 1424-8220

Digital Object Identifier (DOI)

  • 10.3390/s150203706


  • eng