The epidemiology and diagnosis of invasive candidiasis among premature infants.

Journal Article (Journal Article;Review)

Invasive candidiasis is a leading infectious cause of morbidity and mortality in premature infants. Improved recognition of modifiable risk factors and antifungal prophylaxis has contributed to the recent decline in the incidence of this infection among infants. Invasive candidiasis typically occurs in the first 6 weeks of life and presents with nonspecific signs of sepsis. Definitive diagnosis relies on the growth of Candida in blood culture or cultures from other normally sterile sites, but this may identify fewer than half of cases. Improved diagnostics are needed to guide the initiation of antifungal therapy in premature infants.

Full Text

Duke Authors

Cited Authors

  • Kelly, MS; Benjamin, DK; Smith, PB

Published Date

  • March 2015

Published In

Volume / Issue

  • 42 / 1

Start / End Page

  • 105 - ix

PubMed ID

  • 25677999

Pubmed Central ID

  • PMC4328135

Electronic International Standard Serial Number (EISSN)

  • 1557-9840

Digital Object Identifier (DOI)

  • 10.1016/j.clp.2014.10.008


  • eng

Conference Location

  • United States