Antibiotic stewardship: reassessment of guidelines for management of neonatal sepsis.

Journal Article (Journal Article;Review)

In 2010, the Centers for Disease Control and Prevention (CDC) provided updated guidelines for prevention of perinatal group B streptococcus disease. In 2012, the American Academy of Pediatrics' Committee on the Fetus and Newborn (COFN) provided a clinical report which suggested approaches to infants with risk factors for EOS which would increase empirical antibiotic use beyond the CDC guidelines. This Clinics article reviews the CDC guidelines and 2012 COFN report, summarizes the 2014 commentary provided by COFN members which provided a revised clinical algorithm, and discusses mechanisms which could reduce the number of well-appearing term infants exposed to empirical antibiotics.

Full Text

Duke Authors

Cited Authors

  • Cotten, CM

Published Date

  • March 2015

Published In

Volume / Issue

  • 42 / 1

Start / End Page

  • 195 - x

PubMed ID

  • 25678005

Pubmed Central ID

  • PMC4888789

Electronic International Standard Serial Number (EISSN)

  • 1557-9840

Digital Object Identifier (DOI)

  • 10.1016/j.clp.2014.10.007


  • eng

Conference Location

  • United States