The effect of exposure to wood smoke on outcomes of childhood pneumonia in Botswana.
Published
Journal Article
SETTING: Tertiary hospital in Gaborone, Botswana. OBJECTIVE: To examine whether exposure to wood smoke worsens outcomes of childhood pneumonia. DESIGN: Prospective cohort study of children aged 1-23 months meeting clinical criteria for pneumonia. Household use of wood as a cooking fuel was assessed during a face-to-face questionnaire with care givers. We estimated crude and adjusted risk ratios (RRs) and 95% confidence intervals (CIs) for treatment failure at 48 h by household use of wood as a cooking fuel. We assessed for effect modification by age (1-5 vs. 6-23 months) and malnutrition (none vs. moderate vs. severe). RESULTS: The median age of the 284 enrolled children was 5.9 months; 17% had moderate or severe malnutrition. Ninety-nine (35%) children failed treatment at 48 h and 17 (6%) died. In multivariable analyses, household use of wood as a cooking fuel increased the risk of treatment failure at 48 h (RR 1.44, 95%CI 1.09-1.92, P = 0.01). This association differed by child nutritional status (P = 0.02), with a detrimental effect observed only among children with no or moderate malnutrition. CONCLUSIONS: Exposure to wood smoke worsens outcomes for childhood pneumonia. Efforts to prevent exposure to smoke from unprocessed fuels may improve pneumonia outcomes among children.
Full Text
Duke Authors
Cited Authors
- Kelly, MS; Wirth, KE; Madrigano, J; Feemster, KA; Cunningham, CK; Arscott-Mills, T; Boiditswe, S; Shah, SS; Finalle, R; Steenhoff, AP
Published Date
- March 2015
Published In
Volume / Issue
- 19 / 3
Start / End Page
- 349 - 355
PubMed ID
- 25686146
Pubmed Central ID
- 25686146
Electronic International Standard Serial Number (EISSN)
- 1815-7920
Digital Object Identifier (DOI)
- 10.5588/ijtld.14.0557
Language
- eng
Conference Location
- France