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Esophageal and esophagogastric junction cancers, version 1.2015.

Publication ,  Journal Article
Ajani, JA; D'Amico, TA; Almhanna, K; Bentrem, DJ; Besh, S; Chao, J; Das, P; Denlinger, C; Fanta, P; Fuchs, CS; Gerdes, H; Glasgow, RE ...
Published in: J Natl Compr Canc Netw
February 2015
Published version (DOI) Link to item

Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Adenocarcinoma is more common in North America and Western European countries, originating mostly in the lower third of the esophagus, which often involves the esophagogastric junction (EGJ). Recent randomized trials have shown that the addition of preoperative chemoradiation or perioperative chemotherapy to surgery significantly improves survival in patients with resectable cancer. Targeted therapies with trastuzumab and ramucirumab have produced encouraging results in the treatment of advanced or metastatic EGJ adenocarcinomas. Multidisciplinary team management is essential for patients with esophageal and EGJ cancers. This portion of the NCCN Guidelines for Esophageal and EGJ Cancers discusses management of locally advanced adenocarcinoma of the esophagus and EGJ.

Duke Scholars

Thomas Anthony D'Amico
Author Thomas Anthony D'Amico Surgery, Cardiovascular and Thoracic Surgery
Christopher G. Willett
Author Christopher G. Willett Radiation Oncology
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Published In

J Natl Compr Canc Netw

DOI

10.6004/jnccn.2015.0028

EISSN

1540-1413

Publication Date

February 2015

Volume

13

Issue

2

Start / End Page

194 / 227

Location

United States

Related Subject Headings

  • Stomach Neoplasms
  • Oncology & Carcinogenesis
  • Humans
  • Esophagogastric Junction
  • Esophageal Neoplasms
  • 4203 Health services and systems
  • 3211 Oncology and carcinogenesis
 

Citation

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Ajani, J. A., D’Amico, T. A., Almhanna, K., Bentrem, D. J., Besh, S., Chao, J., … National comprehensive cancer network, . (2015). Esophageal and esophagogastric junction cancers, version 1.2015. J Natl Compr Canc Netw, 13(2), 194–227. https://doi.org/10.6004/jnccn.2015.0028
Ajani, Jaffer A., Thomas A. D’Amico, Khaldoun Almhanna, David J. Bentrem, Stephen Besh, Joseph Chao, Prajnan Das, et al. “Esophageal and esophagogastric junction cancers, version 1.2015.” J Natl Compr Canc Netw 13, no. 2 (February 2015): 194–227. https://doi.org/10.6004/jnccn.2015.0028.
Ajani JA, D’Amico TA, Almhanna K, Bentrem DJ, Besh S, Chao J, et al. Esophageal and esophagogastric junction cancers, version 1.2015. J Natl Compr Canc Netw. 2015 Feb;13(2):194–227.
Ajani, Jaffer A., et al. “Esophageal and esophagogastric junction cancers, version 1.2015.” J Natl Compr Canc Netw, vol. 13, no. 2, Feb. 2015, pp. 194–227. Pubmed, doi:10.6004/jnccn.2015.0028.
Ajani JA, D’Amico TA, Almhanna K, Bentrem DJ, Besh S, Chao J, Das P, Denlinger C, Fanta P, Fuchs CS, Gerdes H, Glasgow RE, Hayman JA, Hochwald S, Hofstetter WL, Ilson DH, Jaroszewski D, Jasperson K, Keswani RN, Kleinberg LR, Korn WM, Leong S, Lockhart AC, Mulcahy MF, Orringer MB, Posey JA, Poultsides GA, Sasson AR, Scott WJ, Strong VE, Varghese TK, Washington MK, Willett CG, Wright CD, Zelman D, McMillian N, Sundar H, National comprehensive cancer network. Esophageal and esophagogastric junction cancers, version 1.2015. J Natl Compr Canc Netw. 2015 Feb;13(2):194–227.

Published In

J Natl Compr Canc Netw

DOI

10.6004/jnccn.2015.0028

EISSN

1540-1413

Publication Date

February 2015

Volume

13

Issue

2

Start / End Page

194 / 227

Location

United States

Related Subject Headings

  • Stomach Neoplasms
  • Oncology & Carcinogenesis
  • Humans
  • Esophagogastric Junction
  • Esophageal Neoplasms
  • 4203 Health services and systems
  • 3211 Oncology and carcinogenesis