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Factors associated with high hospital resource use in a population-based study of children with orofacial clefts.

Publication ,  Journal Article
Razzaghi, H; Dawson, A; Grosse, SD; Allori, AC; Kirby, RS; Olney, RS; Correia, J; Cassell, CH
Published in: Birth Defects Res A Clin Mol Teratol
February 2015

BACKGROUND: Little is known about population-based maternal, child, and system characteristics associated with high hospital resource use for children with orofacial clefts (OFC) in the US. METHODS: This was a statewide, population-based, retrospective observational study of children with OFC born between 1998 and 2006, identified by the Florida Birth Defects Registry whose records were linked with longitudinal hospital discharge records. We stratified the descriptive results by cleft type [cleft lip with cleft palate, cleft lip, and cleft palate] and by isolated versus nonisolated OFC (accompanied by other coded major birth defects). We used Poisson regression to analyze associations between selected characteristics and high hospital resource use (≥90th percentile of estimated hospitalized days and inpatient costs) for birth, postbirth, and total hospitalizations initiated before age 2 years. RESULTS: Our analysis included 2,129 children with OFC. Infants who were born low birth weight (<2500 grams) were significantly more likely to have high birth hospitalization costs for CLP (adjusted prevalence ratio: 1.6 [95% confidence interval: 1.0-2.7]), CL (adjusted prevalence ratio: 3.0 [95% confidence interval: 1.1-8.1]), and CP (adjusted prevalence ratio: 2.3 [95% confidence interval: 1.3-4.0]). Presence of multiple birth defects was significantly associated with a three- to eleven-fold and a three- to nine-fold increase in the prevalence of high costs and number of hospitalized days, respectively; at birth, postbirth before age 2 years and overall hospitalizations. CONCLUSION: Children with cleft palate had the greatest hospital resources use. Additionally, the presence of multiple birth defects contributed to greater inpatient days and costs for children with OFC.

Duke Scholars

Published In

Birth Defects Res A Clin Mol Teratol

DOI

EISSN

1542-0760

Publication Date

February 2015

Volume

103

Issue

2

Start / End Page

127 / 143

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Registries
  • Prevalence
  • Male
  • Length of Stay
  • Infant, Low Birth Weight
  • Infant
  • Humans
  • Hospitals
  • Genetics & Heredity
 

Citation

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Chicago
ICMJE
MLA
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Razzaghi, H., Dawson, A., Grosse, S. D., Allori, A. C., Kirby, R. S., Olney, R. S., … Cassell, C. H. (2015). Factors associated with high hospital resource use in a population-based study of children with orofacial clefts. Birth Defects Res A Clin Mol Teratol, 103(2), 127–143. https://doi.org/10.1002/bdra.23356
Razzaghi, Hilda, April Dawson, Scott D. Grosse, Alexander C. Allori, Russell S. Kirby, Richard S. Olney, Jane Correia, and Cynthia H. Cassell. “Factors associated with high hospital resource use in a population-based study of children with orofacial clefts.Birth Defects Res A Clin Mol Teratol 103, no. 2 (February 2015): 127–43. https://doi.org/10.1002/bdra.23356.
Razzaghi H, Dawson A, Grosse SD, Allori AC, Kirby RS, Olney RS, et al. Factors associated with high hospital resource use in a population-based study of children with orofacial clefts. Birth Defects Res A Clin Mol Teratol. 2015 Feb;103(2):127–43.
Razzaghi, Hilda, et al. “Factors associated with high hospital resource use in a population-based study of children with orofacial clefts.Birth Defects Res A Clin Mol Teratol, vol. 103, no. 2, Feb. 2015, pp. 127–43. Pubmed, doi:10.1002/bdra.23356.
Razzaghi H, Dawson A, Grosse SD, Allori AC, Kirby RS, Olney RS, Correia J, Cassell CH. Factors associated with high hospital resource use in a population-based study of children with orofacial clefts. Birth Defects Res A Clin Mol Teratol. 2015 Feb;103(2):127–143.
Journal cover image

Published In

Birth Defects Res A Clin Mol Teratol

DOI

EISSN

1542-0760

Publication Date

February 2015

Volume

103

Issue

2

Start / End Page

127 / 143

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Registries
  • Prevalence
  • Male
  • Length of Stay
  • Infant, Low Birth Weight
  • Infant
  • Humans
  • Hospitals
  • Genetics & Heredity