The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials.
Journal Article (Review)
The novel oral anticoagulants (NOACs) have rapidly emerged as an alternative therapy to warfarin. Several recent phase 3 randomized control trials have demonstrated the efficacy and safety of the NOACs in the treatment for patients with nonvalvular atrial fibrillation. As the NOACs are incorporated in clinical practice, questions have begun to arise concerning their optimal use in commonly encountered situations. In this review, we provide a summary of the available evidence from the phase 3 randomized control trials specifically with regard to 1 such scenario, the periprocedural management of NOACs, with a goal of providing guidance for practicing clinicians.
Full Text
Duke Authors
Cited Authors
- Krishnamoorthy, A; Sherwood, MW; Lopes, RD; Becker, RC
Published Date
- March 2015
Published In
Volume / Issue
- 169 / 3
Start / End Page
- 315 - 322
PubMed ID
- 25728720
Pubmed Central ID
- 25728720
Electronic International Standard Serial Number (EISSN)
- 1097-6744
International Standard Serial Number (ISSN)
- 0002-8703
Digital Object Identifier (DOI)
- 10.1016/j.ahj.2014.12.008
Language
- eng