Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012


Journal Article

© 2014 The Authors. Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that primarily causes respiratory illness. We conducted a seroprevalence study of banked human serum samples collected in 2012 from Southern Saudi Arabia. Sera from 300 animal workers (17% with daily camel exposure) and 50 non-animal-exposed controls were examined for serological evidence of MERS-CoV infection by a pseudoparticle MERS-CoV spike protein neutralization assay. None of the sera reproducibly neutralized the MERS-CoV-pseudotyped lentiviral vector. These data suggest that serological evidence of zoonotic transmission of MERS-CoV was not common among animal workers in Southern Saudi Arabia during July 2012.

Full Text

Duke Authors

Cited Authors

  • Memish, ZA; Alsahly, A; Masri, MA; Heil, GL; Anderson, BD; Peiris, M; Khan, SU; Gray, GC

Published Date

  • January 1, 2015

Published In

Volume / Issue

  • 9 / 2

Start / End Page

  • 64 - 67

Electronic International Standard Serial Number (EISSN)

  • 1750-2659

International Standard Serial Number (ISSN)

  • 1750-2640

Digital Object Identifier (DOI)

  • 10.1111/irv.12287

Citation Source

  • Scopus