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Na+ channel function, regulation, structure, trafficking and sequestration.

Publication ,  Journal Article
Chen-Izu, Y; Shaw, RM; Pitt, GS; Yarov-Yarovoy, V; Sack, JT; Abriel, H; Aldrich, RW; Belardinelli, L; Cannell, MB; Catterall, WA; Chazin, WJ ...
Published in: J Physiol
March 15, 2015

This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation-contraction coupling and arrhythmias: Na(+) channel and Na(+) transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na(+) channel function and regulation, Na(+) channel structure and function, and Na(+) channel trafficking, sequestration and complexing.

Duke Scholars

Published In

J Physiol

DOI

EISSN

1469-7793

Publication Date

March 15, 2015

Volume

593

Issue

6

Start / End Page

1347 / 1360

Location

England

Related Subject Headings

  • Sodium Channels
  • Sodium Channel Blockers
  • Protein Transport
  • Physiology
  • Myocytes, Cardiac
  • Molecular Sequence Data
  • Humans
  • Congresses as Topic
  • Animals
  • Amino Acid Sequence
 

Citation

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Chen-Izu, Y., Shaw, R. M., Pitt, G. S., Yarov-Yarovoy, V., Sack, J. T., Abriel, H., … Bers, D. M. (2015). Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol, 593(6), 1347–1360. https://doi.org/10.1113/jphysiol.2014.281428
Chen-Izu, Ye, Robin M. Shaw, Geoffrey S. Pitt, Vladimir Yarov-Yarovoy, Jon T. Sack, Hugues Abriel, Richard W. Aldrich, et al. “Na+ channel function, regulation, structure, trafficking and sequestration.J Physiol 593, no. 6 (March 15, 2015): 1347–60. https://doi.org/10.1113/jphysiol.2014.281428.
Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, et al. Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol. 2015 Mar 15;593(6):1347–60.
Chen-Izu, Ye, et al. “Na+ channel function, regulation, structure, trafficking and sequestration.J Physiol, vol. 593, no. 6, Mar. 2015, pp. 1347–60. Pubmed, doi:10.1113/jphysiol.2014.281428.
Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, Izu LT, Maier LS, Maltsev VA, Marionneau C, Mohler PJ, Rajamani S, Rasmusson RL, Sobie EA, Clancy CE, Bers DM. Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol. 2015 Mar 15;593(6):1347–1360.
Journal cover image

Published In

J Physiol

DOI

EISSN

1469-7793

Publication Date

March 15, 2015

Volume

593

Issue

6

Start / End Page

1347 / 1360

Location

England

Related Subject Headings

  • Sodium Channels
  • Sodium Channel Blockers
  • Protein Transport
  • Physiology
  • Myocytes, Cardiac
  • Molecular Sequence Data
  • Humans
  • Congresses as Topic
  • Animals
  • Amino Acid Sequence