Tandem gold/silver-catalyzed cycloaddition/hydroarylation of 7-aryl-1,6-enynes to form 6,6-diarylbicyclo[3.2.0]heptanes


Journal Article

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Mixtures of [{PCy2(o-biphenyl)}AuCl] and AgSbF6 catalyze the tandem cycloaddition/hydroarylation of 7-aryl-1,6-enynes with electron-rich arenes to form 6,6-diarylbicyclo[3.2.0]heptanes in good yield under mild conditions. Experimental observations point to a mechanism involving gold-catalyzed cycloaddition followed by silver-catalyzed hydroarylation of a bicyclo[3.2.0]hept-1(7)-ene intermediate.

Full Text

Duke Authors

Cited Authors

  • Robertson, BD; Brooner, REM; Widenhoefer, RA

Published Date

  • April 7, 2015

Published In

Volume / Issue

  • 21 / 15

Start / End Page

  • 5714 - 5717

Electronic International Standard Serial Number (EISSN)

  • 1521-3765

International Standard Serial Number (ISSN)

  • 0947-6539

Digital Object Identifier (DOI)

  • 10.1002/chem.201500371

Citation Source

  • Scopus