Scholars@Duke publication: Ghrelin.

Ghrelin.

Publication , Journal Article

Müller, TD; Nogueiras, R; Andermann, ML; Andrews, ZB; Anker, SD; Argente, J; Batterham, RL; Benoit, SC; Bowers, CY; Broglio, F; Casanueva, FF ...

Published in: Mol Metab

June 2015

Published version (DOI) Open Access Copy (Duke) Link to item

BACKGROUND: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. SCOPE OF REVIEW: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. MAJOR CONCLUSIONS: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.

Duke Scholars

Author David A D'Alessio Medicine, Endocrinology, Metabolism, and Nutrition

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Published In

Mol Metab

DOI

10.1016/j.molmet.2015.03.005

ISSN

2212-8778

Publication Date

June 2015

Volume

Issue

Start / End Page

437 / 460

Location

Germany

Related Subject Headings

3101 Biochemistry and cell biology
0606 Physiology
0601 Biochemistry and Cell Biology

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APA

Chicago

ICMJE

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Müller, T. D., Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., … Tschöp, M. H. (2015). Ghrelin. Mol Metab, 4(6), 437–460. https://doi.org/10.1016/j.molmet.2015.03.005

Müller, T. D., R. Nogueiras, M. L. Andermann, Z. B. Andrews, S. D. Anker, J. Argente, R. L. Batterham, et al. “Ghrelin.” Mol Metab 4, no. 6 (June 2015): 437–60. https://doi.org/10.1016/j.molmet.2015.03.005.

Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, et al. Ghrelin. Mol Metab. 2015 Jun;4(6):437–60.

Müller, T. D., et al. “Ghrelin.” Mol Metab, vol. 4, no. 6, June 2015, pp. 437–60. Pubmed, doi:10.1016/j.molmet.2015.03.005.

Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, Batterham RL, Benoit SC, Bowers CY, Broglio F, Casanueva FF, D’Alessio D, Depoortere I, Geliebter A, Ghigo E, Cole PA, Cowley M, Cummings DE, Dagher A, Diano S, Dickson SL, Diéguez C, Granata R, Grill HJ, Grove K, Habegger KM, Heppner K, Heiman ML, Holsen L, Holst B, Inui A, Jansson JO, Kirchner H, Korbonits M, Laferrère B, LeRoux CW, Lopez M, Morin S, Nakazato M, Nass R, Perez-Tilve D, Pfluger PT, Schwartz TW, Seeley RJ, Sleeman M, Sun Y, Sussel L, Tong J, Thorner MO, van der Lely AJ, van der Ploeg LHT, Zigman JM, Kojima M, Kangawa K, Smith RG, Horvath T, Tschöp MH. Ghrelin. Mol Metab. 2015 Jun;4(6):437–460.

Published In

Mol Metab

DOI

10.1016/j.molmet.2015.03.005

ISSN

2212-8778

Publication Date

June 2015

Volume

Issue

Start / End Page

437 / 460

Location

Germany

Related Subject Headings

3101 Biochemistry and cell biology
0606 Physiology
0601 Biochemistry and Cell Biology