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Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment

Publication ,  Journal Article
Bialas, KM; Swamy, GK; Permar, SR
Published in: NeoReviews
January 1, 2015

Mother-to-child transmission of cytomegalovirus (CMV) can lead to severe birth defects and neurologic impairment of infants. Congenital CMV is the most common congenital infection and the leading infectious cause of infant hearing loss and neurologic deficits, complicating up to 2% of all pregnancies globally. Although antiviral treatment of congenitally CMV-infected infants can ameliorate CMV-associated hearing loss and developmental delay, interventions that can effectively prevent congenital CMV infection and the associated neurologic impairments are still being evaluated. Moreover, an effective CMV vaccine to protect mothers against CMV acquisition during pregnancy is urgently needed to reduce the sizeable health and economic burden of this disease. Active and passive maternal and infant immunization strategies to prevent symptomatic perinatal CMV infection are a critical need in pediatric health.

Duke Scholars

Published In

NeoReviews

DOI

EISSN

1526-9906

Publication Date

January 1, 2015

Volume

16

Issue

4

Start / End Page

e231 / e235

Related Subject Headings

  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bialas, K. M., Swamy, G. K., & Permar, S. R. (2015). Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment. NeoReviews, 16(4), e231–e235. https://doi.org/10.1542/neo.16-4-e231
Bialas, K. M., G. K. Swamy, and S. R. Permar. “Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment.” NeoReviews 16, no. 4 (January 1, 2015): e231–35. https://doi.org/10.1542/neo.16-4-e231.
Bialas KM, Swamy GK, Permar SR. Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment. NeoReviews. 2015 Jan 1;16(4):e231–5.
Bialas, K. M., et al. “Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment.” NeoReviews, vol. 16, no. 4, Jan. 2015, pp. e231–35. Scopus, doi:10.1542/neo.16-4-e231.
Bialas KM, Swamy GK, Permar SR. Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment. NeoReviews. 2015 Jan 1;16(4):e231–e235.

Published In

NeoReviews

DOI

EISSN

1526-9906

Publication Date

January 1, 2015

Volume

16

Issue

4

Start / End Page

e231 / e235

Related Subject Headings

  • 3202 Clinical sciences
  • 1103 Clinical Sciences