Retinal representation of the elementary visual signal.

Published

Journal Article

The propagation of visual signals from individual cone photoreceptors through parallel neural circuits was examined in the primate retina. Targeted stimulation of individual cones was combined with simultaneous recording from multiple retinal ganglion cells of identified types. The visual signal initiated by an individual cone produced strong responses with different kinetics in three of the four numerically dominant ganglion cell types. The magnitude and kinetics of light responses in each ganglion cell varied nonlinearly with stimulus strength but in a manner that was independent of the cone of origin after accounting for the overall input strength of each cone. Based on this property of independence, the receptive field profile of an individual ganglion cell could be well estimated from responses to stimulation of each cone individually. Together, these findings provide a quantitative account of how elementary visual inputs form the ganglion cell receptive field.

Full Text

Duke Authors

Cited Authors

  • Li, PH; Field, GD; Greschner, M; Ahn, D; Gunning, DE; Mathieson, K; Sher, A; Litke, AM; Chichilnisky, EJ

Published Date

  • January 8, 2014

Published In

Volume / Issue

  • 81 / 1

Start / End Page

  • 130 - 139

PubMed ID

  • 24411737

Pubmed Central ID

  • 24411737

Electronic International Standard Serial Number (EISSN)

  • 1097-4199

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2013.10.043

Language

  • eng

Conference Location

  • United States