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The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging.

Publication ,  Conference
Vejdani-Jahromi, M; Kiplagat, A; Trahey, GE; Wolf, PD
Published in: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
January 2014

The possibility of measuring cardiac function noninvasively has generated wide interest in elastography imaging techniques. Shear Wave Elasticity Imaging (SWEI) is an ultrasound-based elastography technique used to measure stiffness of tissues. While this technique has been studied extensively in static homogenous tissues such as liver, breast or prostate, there is still a significant need to study its capabilities to measure cardiac stiffness and function. In this research, we have studied the potential of SWEI to evaluate the coronary perfusion pressure effect on systolic and diastolic stiffness referred to as elastance and compliance of the heart. Five isolated rabbit hearts were used in this study in a Langendorff preparation. SWEI measurements of stiffness were recorded in two steps. In the first step, coronary perfusion was set to normal and then was reduced to half-normal. After 40 minutes of half-normal perfusion, it was returned to normal perfusion for the second step. SWEI velocity decreased from 6.003 m/s to 4.713 m/s in systole and from 1.948 m/s to 1.507 m/s in diastole in the first step. During the second step raising the perfusion to normal, SWEI stiffness showed an increase from 3.760 m/s to 5.468 m/s in systole and from 1.678 m/s to 2.156 m/s during diastole. Our results show that SWEI measurements of stiffness can characterize the cross talk between coronary perfusion and cardiac stiffness and also has the potential to measure compliance and elastance of the heart in systole and diastole.

Duke Scholars

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

DOI

EISSN

2694-0604

ISSN

2375-7477

Publication Date

January 2014

Volume

2014

Start / End Page

5072 / 5075

Related Subject Headings

  • Systole
  • Rabbits
  • Heart Diseases
  • Heart
  • Elasticity Imaging Techniques
  • Echocardiography
  • Diastole
  • Coronary Circulation
  • Compliance
  • Animals
 

Citation

APA
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ICMJE
MLA
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Vejdani-Jahromi, M., Kiplagat, A., Trahey, G. E., & Wolf, P. D. (2014). The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging. In Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference (Vol. 2014, pp. 5072–5075). https://doi.org/10.1109/embc.2014.6944765
Vejdani-Jahromi, Maryam, Annette Kiplagat, Gregg E. Trahey, and Patrick D. Wolf. “The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging.” In Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2014:5072–75, 2014. https://doi.org/10.1109/embc.2014.6944765.
Vejdani-Jahromi M, Kiplagat A, Trahey GE, Wolf PD. The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging. In: Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference. 2014. p. 5072–5.
Vejdani-Jahromi, Maryam, et al. “The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, vol. 2014, 2014, pp. 5072–75. Epmc, doi:10.1109/embc.2014.6944765.
Vejdani-Jahromi M, Kiplagat A, Trahey GE, Wolf PD. The effect of acute coronary perfusion change on cardiac function measured by Shear Wave Elasticity Imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference. 2014. p. 5072–5075.

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

DOI

EISSN

2694-0604

ISSN

2375-7477

Publication Date

January 2014

Volume

2014

Start / End Page

5072 / 5075

Related Subject Headings

  • Systole
  • Rabbits
  • Heart Diseases
  • Heart
  • Elasticity Imaging Techniques
  • Echocardiography
  • Diastole
  • Coronary Circulation
  • Compliance
  • Animals