Skip to main content
Journal cover image

The management of acute coronary syndromes in patients with chronic kidney disease.

Publication ,  Journal Article
Roberts, JK; McCullough, PA
Published in: Adv Chronic Kidney Dis
November 2014

Coronary heart disease is highly prevalent in patients with CKD, and survival after acute coronary syndrome (ACS) is worse compared with the general population. Many trials that define guidelines for cardiovascular disease excluded patients with kidney disease, leaving a gap between the evidence base and clinical reality. The underlying pathophysiology of vascular disease appears to be different in the setting of CKD. Patients with CKD are more likely to present with myocardial infarction and less likely to be diagnosed with ACS on admission compared with the general population. Patients with CKD appear to benefit with angiography and revascularization compared with medical management alone. However, the increased risk of in-hospital bleeding and risk of contrast-induced acute kidney injury are 2 factors that can limit overall benefit for some. Thus, judicious application of available therapies for the management of ACS is warranted to extend survival and reduce hospitalizations in this high-risk population. In this review, we highlight the clinical challenges and potential solutions for managing ACS in patients with CKD.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Adv Chronic Kidney Dis

DOI

EISSN

1548-5609

Publication Date

November 2014

Volume

21

Issue

6

Start / End Page

472 / 479

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Renal Insufficiency, Chronic
  • Radiography
  • Platelet Aggregation Inhibitors
  • Patient Care Team
  • Myocardial Revascularization
  • Humans
  • Hemorrhage
  • Fibrinolytic Agents
  • Contrast Media
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Roberts, J. K., & McCullough, P. A. (2014). The management of acute coronary syndromes in patients with chronic kidney disease. Adv Chronic Kidney Dis, 21(6), 472–479. https://doi.org/10.1053/j.ackd.2014.08.005
Roberts, John K., and Peter A. McCullough. “The management of acute coronary syndromes in patients with chronic kidney disease.Adv Chronic Kidney Dis 21, no. 6 (November 2014): 472–79. https://doi.org/10.1053/j.ackd.2014.08.005.
Roberts JK, McCullough PA. The management of acute coronary syndromes in patients with chronic kidney disease. Adv Chronic Kidney Dis. 2014 Nov;21(6):472–9.
Roberts, John K., and Peter A. McCullough. “The management of acute coronary syndromes in patients with chronic kidney disease.Adv Chronic Kidney Dis, vol. 21, no. 6, Nov. 2014, pp. 472–79. Pubmed, doi:10.1053/j.ackd.2014.08.005.
Roberts JK, McCullough PA. The management of acute coronary syndromes in patients with chronic kidney disease. Adv Chronic Kidney Dis. 2014 Nov;21(6):472–479.
Journal cover image

Published In

Adv Chronic Kidney Dis

DOI

EISSN

1548-5609

Publication Date

November 2014

Volume

21

Issue

6

Start / End Page

472 / 479

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Renal Insufficiency, Chronic
  • Radiography
  • Platelet Aggregation Inhibitors
  • Patient Care Team
  • Myocardial Revascularization
  • Humans
  • Hemorrhage
  • Fibrinolytic Agents
  • Contrast Media