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The expanding implications of polyploidy.

Publication ,  Journal Article
Schoenfelder, KP; Fox, DT
Published in: J Cell Biol
May 25, 2015

Polyploid cells, which contain more than two genome copies, occur throughout nature. Beyond well-established roles in increasing cell size/metabolic output, polyploidy can also promote nonuniform genome, transcriptome, and metabolome alterations. Polyploidy also frequently confers resistance to environmental stresses not tolerated by diploid cells. Recent progress has begun to unravel how this fascinating phenomenon contributes to normal physiology and disease.

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Published In

J Cell Biol

DOI

EISSN

1540-8140

Publication Date

May 25, 2015

Volume

209

Issue

4

Start / End Page

485 / 491

Location

United States

Related Subject Headings

  • Transcriptome
  • Polyploidy
  • Humans
  • Genome
  • Gene Dosage
  • Developmental Biology
  • Animals
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
 

Citation

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Schoenfelder, K. P., & Fox, D. T. (2015). The expanding implications of polyploidy. J Cell Biol, 209(4), 485–491. https://doi.org/10.1083/jcb.201502016
Schoenfelder, Kevin P., and Donald T. Fox. “The expanding implications of polyploidy.J Cell Biol 209, no. 4 (May 25, 2015): 485–91. https://doi.org/10.1083/jcb.201502016.
Schoenfelder KP, Fox DT. The expanding implications of polyploidy. J Cell Biol. 2015 May 25;209(4):485–91.
Schoenfelder, Kevin P., and Donald T. Fox. “The expanding implications of polyploidy.J Cell Biol, vol. 209, no. 4, May 2015, pp. 485–91. Pubmed, doi:10.1083/jcb.201502016.
Schoenfelder KP, Fox DT. The expanding implications of polyploidy. J Cell Biol. 2015 May 25;209(4):485–491.

Published In

J Cell Biol

DOI

EISSN

1540-8140

Publication Date

May 25, 2015

Volume

209

Issue

4

Start / End Page

485 / 491

Location

United States

Related Subject Headings

  • Transcriptome
  • Polyploidy
  • Humans
  • Genome
  • Gene Dosage
  • Developmental Biology
  • Animals
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences