The expanding implications of polyploidy.

Journal Article (Journal Article;Review)

Polyploid cells, which contain more than two genome copies, occur throughout nature. Beyond well-established roles in increasing cell size/metabolic output, polyploidy can also promote nonuniform genome, transcriptome, and metabolome alterations. Polyploidy also frequently confers resistance to environmental stresses not tolerated by diploid cells. Recent progress has begun to unravel how this fascinating phenomenon contributes to normal physiology and disease.

Full Text

Duke Authors

Cited Authors

  • Schoenfelder, KP; Fox, DT

Published Date

  • May 25, 2015

Published In

Volume / Issue

  • 209 / 4

Start / End Page

  • 485 - 491

PubMed ID

  • 26008741

Pubmed Central ID

  • PMC4442802

Electronic International Standard Serial Number (EISSN)

  • 1540-8140

Digital Object Identifier (DOI)

  • 10.1083/jcb.201502016


  • eng

Conference Location

  • United States