Elucidating the links between endocrine disruptors and neurodevelopment.

Journal Article (Journal Article)

Recent data indicate that approximately 12% of children in the United States are affected by neurodevelopmental disorders, including attention deficit hyperactivity disorder, learning disorders, intellectual disabilities, and autism spectrum disorders. Accumulating evidence indicates a multifactorial etiology for these disorders, with social, physical, genetic susceptibility, nutritional factors, and chemical toxicants acting together to influence risk. Exposure to endocrine-disrupting chemicals during the early stages of life can disrupt normal patterns of development and thus alter brain function and disease susceptibility later in life. This article highlights research efforts and pinpoints approaches that could shed light on the possible associations between environmental chemicals that act on the endocrine system and compromised neurodevelopmental outcomes.

Full Text

Duke Authors

Cited Authors

  • Schug, TT; Blawas, AM; Gray, K; Heindel, JJ; Lawler, CP

Published Date

  • June 2015

Published In

Volume / Issue

  • 156 / 6

Start / End Page

  • 1941 - 1951

PubMed ID

  • 25714811

Pubmed Central ID

  • PMC5393340

Electronic International Standard Serial Number (EISSN)

  • 1945-7170

International Standard Serial Number (ISSN)

  • 0013-7227

Digital Object Identifier (DOI)

  • 10.1210/en.2014-1734


  • eng