Elucidating the links between endocrine disruptors and neurodevelopment.
Journal Article (Journal Article)
Recent data indicate that approximately 12% of children in the United States are affected by neurodevelopmental disorders, including attention deficit hyperactivity disorder, learning disorders, intellectual disabilities, and autism spectrum disorders. Accumulating evidence indicates a multifactorial etiology for these disorders, with social, physical, genetic susceptibility, nutritional factors, and chemical toxicants acting together to influence risk. Exposure to endocrine-disrupting chemicals during the early stages of life can disrupt normal patterns of development and thus alter brain function and disease susceptibility later in life. This article highlights research efforts and pinpoints approaches that could shed light on the possible associations between environmental chemicals that act on the endocrine system and compromised neurodevelopmental outcomes.
Full Text
Duke Authors
Cited Authors
- Schug, TT; Blawas, AM; Gray, K; Heindel, JJ; Lawler, CP
Published Date
- June 2015
Published In
Volume / Issue
- 156 / 6
Start / End Page
- 1941 - 1951
PubMed ID
- 25714811
Pubmed Central ID
- 25714811
Electronic International Standard Serial Number (EISSN)
- 1945-7170
International Standard Serial Number (ISSN)
- 0013-7227
Digital Object Identifier (DOI)
- 10.1210/en.2014-1734
Language
- eng