Skip to main content
Journal cover image

Point of care and factor concentrate-based coagulation algorithms.

Publication ,  Other
Theusinger, OM; Stein, P; Levy, JH
Published in: Transfus Med Hemother
March 2015

In the last years it has become evident that the use of blood products should be reduced whenever possible. There is increasing evidence regarding serious adverse events, including higher mortality and morbidity, related to transfusions. The use of point of care (POC) devices integrated in algorithms is one of the important mechanisms to limit blood product exposure. Any type of algorithm, especially the POC-based ones, allows goal-directed transfusions of blood products and even better targeted factor concentrate substitutions. Different types of algorithms in different surgical settings (cardiac surgery, trauma, liver surgery etc.) have been established with growing interest in their use as they offer objective therapy for management and reduction of blood product use. The use of POC devices with evidence-based algorithms is important in the bleeding patient independent of its origin (traumatic vs. surgical). The use of factor concentrates compared to the classical blood products can be cost-saving, beneficial for the patient, and in agreement with the WHO-requested standard of care. The empiric and uncontrolled use of blood products such as fresh frozen plasma, red blood cells, and platelets without POC monitoring should no longer be followed with regard to actual evidence in literature. Furthermore, the use of factor concentrates may provide better outcomes and potential for cost saving.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Transfus Med Hemother

DOI

ISSN

1660-3796

Publication Date

March 2015

Volume

42

Issue

2

Start / End Page

115 / 121

Location

Switzerland

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Theusinger, O. M., Stein, P., & Levy, J. H. (2015). Point of care and factor concentrate-based coagulation algorithms. Transfus Med Hemother. Switzerland. https://doi.org/10.1159/000381320
Theusinger, Oliver M., Philipp Stein, and Jerrold H. Levy. “Point of care and factor concentrate-based coagulation algorithms.Transfus Med Hemother, March 2015. https://doi.org/10.1159/000381320.
Theusinger OM, Stein P, Levy JH. Point of care and factor concentrate-based coagulation algorithms. Vol. 42, Transfus Med Hemother. 2015. p. 115–21.
Theusinger, Oliver M., et al. “Point of care and factor concentrate-based coagulation algorithms.Transfus Med Hemother, vol. 42, no. 2, Mar. 2015, pp. 115–21. Pubmed, doi:10.1159/000381320.
Theusinger OM, Stein P, Levy JH. Point of care and factor concentrate-based coagulation algorithms. Transfus Med Hemother. 2015. p. 115–121.
Journal cover image

Published In

Transfus Med Hemother

DOI

ISSN

1660-3796

Publication Date

March 2015

Volume

42

Issue

2

Start / End Page

115 / 121

Location

Switzerland

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences