Antiplatelet Therapy in Cardiovascular Disease
Light Transmission Aggregometry
Publication
, Chapter
Gurbel, PA; Gesheff, M; Bliden, KP; Tantry, US
June 3, 2014
Laboratory evaluation of platelet function by a simple and reliable in vitro method is crucial to understand the critical role of platelets during hemostasis and thrombotic complications of cardiovascular disease. An in vitro quantitative determination of platelet aggregation by the light transmittance aggregometry (LTA) and the important role of adenosine diphosphate (ADP) during platelet aggregation were first described by Born. Despite its limitations, LTA is still considered as the "gold standard assay" for platelet function measurement. In addition to the assessment of antiplatelet drug response, LTA is also used to study bleeding disorders and congenital or acquired disorders of platelet receptors.
Duke Scholars
DOI
ISBN
9781118275757
Publication Date
June 3, 2014
Start / End Page
51 / 57
Citation
APA
Chicago
ICMJE
MLA
NLM
Gurbel, P. A., Gesheff, M., Bliden, K. P., & Tantry, U. S. (2014). Light Transmission Aggregometry. In Antiplatelet Therapy in Cardiovascular Disease (pp. 51–57). https://doi.org/10.1002/9781118493984.ch7
Gurbel, P. A., M. Gesheff, K. P. Bliden, and U. S. Tantry. “Light Transmission Aggregometry.” In Antiplatelet Therapy in Cardiovascular Disease, 51–57, 2014. https://doi.org/10.1002/9781118493984.ch7.
Gurbel PA, Gesheff M, Bliden KP, Tantry US. Light Transmission Aggregometry. In: Antiplatelet Therapy in Cardiovascular Disease. 2014. p. 51–7.
Gurbel, P. A., et al. “Light Transmission Aggregometry.” Antiplatelet Therapy in Cardiovascular Disease, 2014, pp. 51–57. Scopus, doi:10.1002/9781118493984.ch7.
Gurbel PA, Gesheff M, Bliden KP, Tantry US. Light Transmission Aggregometry. Antiplatelet Therapy in Cardiovascular Disease. 2014. p. 51–57.
DOI
ISBN
9781118275757
Publication Date
June 3, 2014
Start / End Page
51 / 57