Epidemiology, Evolution, and Recent Outbreaks of Avian Influenza Virus in China.

Journal Article (Journal Article;Review)

Novel reassortants of H7N9, H10N8, and H5N6 avian influenza viruses (AIVs) are currently circulating in China's poultry flocks, occasionally infecting humans and other mammals. Combined with the sometimes enzootic H5N1 and H9N2 strains, this cauldron of genetically diverse AIVs pose significant risks to public health. Here, we review the epidemiology, evolution, and recent outbreaks of AIVs in China, discuss reasons behind the recent increase in the emergence of novel AIVs, and identify warning signs which may point to the emergence of a potentially virulent and highly transmissible AIV to humans. This review will be useful to authorities who consider options for the detection and control of AIV transmission in animals and humans, with the goal of preventing future epidemics and pandemics.

Full Text

Duke Authors

Cited Authors

  • Su, S; Bi, Y; Wong, G; Gray, GC; Gao, GF; Li, S

Published Date

  • September 2015

Published In

Volume / Issue

  • 89 / 17

Start / End Page

  • 8671 - 8676

PubMed ID

  • 26063419

Pubmed Central ID

  • PMC4524075

Electronic International Standard Serial Number (EISSN)

  • 1098-5514

Digital Object Identifier (DOI)

  • 10.1128/JVI.01034-15


  • eng

Conference Location

  • United States