Optimization of a coded aperture coherent scatter spectral imaging system for medical imaging

Published

Conference Paper

© 2015 SPIE. Coherent scatter X-ray imaging is a technique that provides spatially-resolved information about the molecular structure of the material under investigation, yielding material-specific contrast that can aid medical diagnosis and inform treatment. In this study, we demonstrate a coherent-scatter imaging approach based on the use of coded apertures (known as coded aperture coherent scatter spectral imaging1, 2) that enables fast, dose-efficient, high-resolution scatter imaging of biologically-relevant materials. Specifically, we discuss how to optimize a coded aperture coherent scatter imaging system for a particular set of objects and materials, describe and characterize our experimental system, and use the system to demonstrate automated material detection in biological tissue.

Full Text

Duke Authors

Cited Authors

  • Greenberg, JA; Lakshmanan, MN; Brady, DJ; Kapadia, AJ

Published Date

  • January 1, 2015

Published In

Volume / Issue

  • 9412 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781628415025

Digital Object Identifier (DOI)

  • 10.1117/12.2082110

Citation Source

  • Scopus