Sensory and circuit mechanisms mediating lower urinary tract reflexes.

Journal Article (Review;Journal Article)

Neural control of continence and micturition is distributed over a network of interconnected reflexes. These reflexes integrate sensory information from the bladder and urethra and are modulated by descending influences to produce different physiological outcomes based on the information arriving from peripheral afferents. Therefore, the mode of activation of primary afferents is essential in understanding the action of spinal reflex pathways in the lower urinary tract. We present an overview of sensory mechanisms in the bladder and urethra focusing on their spinal integration, identify the cardinal spinal reflexes responsible for continence and micturition, and describe how their functional role is controlled via peripheral afferent activity.

Full Text

Duke Authors

Cited Authors

  • Danziger, ZC; Grill, WM

Published Date

  • October 2016

Published In

Volume / Issue

  • 200 /

Start / End Page

  • 21 - 28

PubMed ID

  • 26119358

Pubmed Central ID

  • PMC4670817

Electronic International Standard Serial Number (EISSN)

  • 1872-7484

International Standard Serial Number (ISSN)

  • 1566-0702

Digital Object Identifier (DOI)

  • 10.1016/j.autneu.2015.06.004


  • eng