Trajectories of Obesity and Overweight Rates Among Survivors of Childhood Acute Lymphoblastic Leukemia.

Journal Article (Journal Article)


To describe the trajectories of obesity/overweight rates by age group among survivors of childhood acute lymphoblastic leukemia (ALL) from diagnosis through several years post-therapy.


Longitudinal, descriptive.


Hematology/oncology clinic in the southwestern United States.


62 child and adolescent ALL survivors receiving treatment and follow-up care from 1999-2013.


Retrospective chart review of height, weight, and body mass index.

Main research variables

Annual obesity/overweight rates and developmental age groups.


Different trajectories of obesity/overweight rates existed among age groups. Forty-seven percent of adolescents met the Centers for Disease Control and Prevention criteria for obesity/overweight status at some point following diagnosis, compared to 68% of school-age and 73% of preschool children. Preschool children demonstrated the most rapid rate increase following diagnosis, with a particularly susceptible period in the years immediately following therapy. Obesity/overweight persistence was most characteristic of school-age children.


Important variations in rate and pattern of weight status trajectories exist by age group, demonstrating that children diagnosed with ALL during the preschool and school-age developmental years have the greatest vulnerability of developing obesity/overweight status.

Implications for nursing

Obesity/overweight prevention efforts are greatly needed in children with ALL, and efforts should occur before ALL treatment completion in preschool and school-age children.

Full Text

Duke Authors

Cited Authors

  • Winkler, MR; Hockenberry, MJ; McCarthy, KS; Silva, SG

Published Date

  • July 2015

Published In

Volume / Issue

  • 42 / 4

Start / End Page

  • E287 - E293

PubMed ID

  • 26148325

Electronic International Standard Serial Number (EISSN)

  • 1538-0688

International Standard Serial Number (ISSN)

  • 0190-535X

Digital Object Identifier (DOI)

  • 10.1188/15.onf.e287-e293


  • eng