Performance comparison of breast imaging modalities using a 4AFC human observer study


Conference Paper

© 2015 SPIE. This work compares the visibility of spheres and simulated masses in 2D-mammography and tomosynthesis systems using human observer studies. Performing comparison studies between breast imaging systems poses a number of practical challenges within a clinical environment. We therefore adopted a simulation approach which included synthetic breast blocks, a validated lesion simulation model and a set of validated image modelling tools as a viable alternative to clinical trials. A series of 4-alternative forced choice (4AFC) human observer experiments has been conducted for signal detection tasks using masses and spheres as targets. Five physicists participated in the study viewing images with a 5mm target at a range of contrast levels and 60 trials per experimental condition. The results showed that tomosynthesis has a lower threshold contrast than 2D-mammography for masses and spheres, and that detection studies using spheres may produce overly-optimistic threshold contrast values.

Full Text

Duke Authors

Cited Authors

  • Elangovan, P; Rashidnasab, A; Mackenzie, A; Dance, DR; Young, KC; Bosmans, H; Segars, WP; Wells, K

Published Date

  • January 1, 2015

Published In

Volume / Issue

  • 9412 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781628415025

Digital Object Identifier (DOI)

  • 10.1117/12.2081878

Citation Source

  • Scopus