Herpes Zoster Vaccination: Controversies and Common Clinical Questions.


Journal Article

Herpes zoster, clinically referred to as shingles, is an acute, cutaneous viral infection caused by reactivation of the varicella zoster virus, the same virus that causes chickenpox. The incidence of herpes zoster and its complications increase with decline in cell-mediated immunity, including age-associated decline. The most effective management strategy for herpes zoster is prevention of the disease through vaccination in those who are most vulnerable. Despite the demonstrated efficacy in reducing the incidence and severity of herpes zoster, the uptake of vaccine remains low. Here, we will discuss the controversies that surround the live herpes zoster vaccine and address the common clinical questions that arise. We will also discuss the new adjuvanted herpes zoster vaccine currently under investigation.

Full Text

Duke Authors

Cited Authors

  • Van Epps, P; Schmader, KE; Canaday, DH

Published Date

  • 2016

Published In

Volume / Issue

  • 62 / 2

Start / End Page

  • 150 - 154

PubMed ID

  • 26184711

Pubmed Central ID

  • 26184711

Electronic International Standard Serial Number (EISSN)

  • 1423-0003

Digital Object Identifier (DOI)

  • 10.1159/000431374


  • eng

Conference Location

  • Switzerland