Intensity-modulated radiotherapy


Book Section

© 2013 Springer-Verlag London. All rights are reserved. Intensity-modulated radiotherapy (IMRT) is a radiation delivery technique that allows dose sculpting to improve target coverage while sparing normal tissues. In an IMRT plan, the number of photons delivered (or fluence) varies within a field. Such variability can be used to avoid normal structures with lower radiation tolerance than the cancer and increases the ability to provide focal treatment. It does require significant quality assurance and consideration of patient setup and target motion to ensure treatment accuracy. While the technique itself is not more efficacious in achieving biochemical control, its ability to spare normal tissues allows for dose escalation, which does provide improved prostate cancer control. For prostate cancer, the cancer control benefit of dose escalation has driven a widespread adoption of IMRT for definitive external beam radiotherapy.

Full Text

Duke Authors

Cited Authors

  • Koontz, BF; Godfrey, D; Lee, WR

Published Date

  • July 1, 2013

Book Title

  • Prostate Cancer: A Comprehensive Perspective

Start / End Page

  • 749 - 759

International Standard Book Number 10 (ISBN-10)

  • 144712863X

International Standard Book Number 13 (ISBN-13)

  • 9781447128632

Digital Object Identifier (DOI)

  • 10.1007/978-1-4471-2864-9_63

Citation Source

  • Scopus