Reaffirmed limitations of meta-analytic methods in the study of mild traumatic brain injury: a response to Rohling et al.


Journal Article

In 2009 Pertab, James, and Bigler published a critique of two prior meta-analyses by Binder, Rohling, and Larrabee (1997) and Frencham, Fox, and Maybery (2005) that showed small effect size difference at least 3 months post-injury in individuals who had sustained a mild traumatic brain injury (mTBI). The Binder et al. and Frencham et al. meta-analyses have been widely cited as showing no lasting effect of mTBI. In their critique Pertab et al. (2009) point out many limitations of these two prior meta-analyses, demonstrating that depending on how inclusion/exclusion criteria were defined different meta-analytic findings occur, some supporting the persistence of neuropsychological impairments beyond 3 months. Rohling et al. (2011) have now critiqued Pertab et al. (2009). Herein we respond to the Rolling et al. (2011) critique reaffirming the original findings of Pertab et al. (2009), providing additional details concerning the flaws in prior meta-analytic mTBI studies and the effects on neuropsychological performance.

Full Text

Duke Authors

Cited Authors

  • Bigler, ED; Farrer, TJ; Pertab, JL; James, K; Petrie, JA; Hedges, DW

Published Date

  • 2013

Published In

Volume / Issue

  • 27 / 2

Start / End Page

  • 176 - 214

PubMed ID

  • 23356775

Pubmed Central ID

  • 23356775

Electronic International Standard Serial Number (EISSN)

  • 1744-4144

Digital Object Identifier (DOI)

  • 10.1080/13854046.2012.693950


  • eng

Conference Location

  • England