Cardiovascular Stem Cells in Regenerative Medicine: Ready for Prime Time?

Journal Article (Journal Article)

Restoration of cardiovascular function is the ultimate goal of stem cell-based therapy. In principle, cardiovascular stem cells can improve cardiac function via de novo cardiomyogenesis, enhanced myocardial neovascularization, and prevention of post-infarct remodeling. Stem cell transplantation to improve cardiac function has received mixed results in human clinical trials. These early data suggest that a critical reassessment of the scientific basis to stem cell-based therapy is needed in order to bring this highly promising treatment modality to mainstream clinical care.

Full Text

Duke Authors

Cited Authors

  • Liu, Y-H; Karra, R; Wu, SM

Published Date

  • 2008

Published In

Volume / Issue

  • 5 / 4

Start / End Page

  • 201 - 207

PubMed ID

  • 20054428

Pubmed Central ID

  • PMC2801905

International Standard Serial Number (ISSN)

  • 1740-6773

Digital Object Identifier (DOI)

  • 10.1016/j.ddstr.2008.12.003


  • eng

Conference Location

  • Netherlands