Opioid-Based Analgesia: Impact on Total Joint Arthroplasty.

Journal Article (Journal Article)

The objective of this study was to characterize the impact of opioid-based analgesia in total joint arthroplasty. The primary outcomes were incidence of in-hospital complications, length of stay, and discharge destination. Six hundred and seventy-three primary total hip and knee arthroplasties were retrospectively reviewed. The incidence of opioid-related adverse drug events was 8.5%, which accounted for 58.2% of all postoperative complications. Age, anesthesia technique, ASA score, and surgery type were significant risk factors for complications. After adjusting for these confounders, opioid-related adverse drug events were significantly associated with increased length of stay (P < 0.001) and discharge to extended care facilities (P = 0.014).

Full Text

Duke Authors

Cited Authors

  • Halawi, MJ; Vovos, TJ; Green, CL; Wellman, SS; Attarian, DE; Bolognesi, MP

Published Date

  • December 2015

Published In

Volume / Issue

  • 30 / 12

Start / End Page

  • 2360 - 2363

PubMed ID

  • 26220104

Pubmed Central ID

  • 26220104

Electronic International Standard Serial Number (EISSN)

  • 1532-8406

Digital Object Identifier (DOI)

  • 10.1016/j.arth.2015.06.046


  • eng

Conference Location

  • United States