Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable.

Journal Article (Journal Article)

Genomic research has generated much new knowledge into mechanisms of human disease, with the potential to catalyze novel drug discovery and development, prenatal and neonatal screening, clinical pharmacogenomics, more sensitive risk prediction, and enhanced diagnostics. Genomic medicine, however, has been limited by critical evidence gaps, especially those related to clinical utility and applicability to diverse populations. Genomic medicine may have the greatest impact on health care if it is integrated into primary care, where most health care is received and where evidence supports the value of personalized medicine grounded in continuous healing relationships. Redesigned primary care is the most relevant setting for clinically useful genomic medicine research. Taking insights gained from the activities of the Institute of Medicine (IOM) Roundtable on Translating Genomic-Based Research for Health, we apply lessons learned from the patient-centered medical home national experience to implement genomic medicine in a patient-centered, learning health care system.

Full Text

Duke Authors

Cited Authors

  • David, SP; Johnson, SG; Berger, AC; Feero, WG; Terry, SF; Green, LA; Phillips, RL; Ginsburg, GS

Published Date

  • 2015

Published In

Volume / Issue

  • 13 / 4

Start / End Page

  • 373 - 380

PubMed ID

  • 26195686

Pubmed Central ID

  • PMC4508182

Electronic International Standard Serial Number (EISSN)

  • 1544-1717

Digital Object Identifier (DOI)

  • 10.1370/afm.1772


  • eng

Conference Location

  • United States