The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.


Journal Article

By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA index values ≥3.0 had a positive predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease, making a supplemental Western immunoblot potentially unnecessary.

Full Text

Duke Authors

Cited Authors

  • Lipsett, SC; Pollock, NR; Branda, JA; Gordon, CD; Gordon, CR; Lantos, PM; Nigrovic, LE

Published Date

  • November 2015

Published In

Volume / Issue

  • 34 / 11

Start / End Page

  • 1260 - 1262

PubMed ID

  • 26222064

Pubmed Central ID

  • 26222064

Electronic International Standard Serial Number (EISSN)

  • 1532-0987

Digital Object Identifier (DOI)

  • 10.1097/INF.0000000000000858


  • eng

Conference Location

  • United States