Ecological Drivers of Virus Evolution: Astrovirus as a Case Study.


Journal Article (Review)

Although RNA viruses exhibit a high frequency of host jumps, major differences exist among the different virus families. Astroviruses infect a wide range of hosts, affecting both public health systems and economic production chains. Here we delineate the ecological and adaptive processes that drive the cross-species transmission of astroviruses. We observe that distinct transmission zones determine the prevailing astrovirus host and virus diversity, which in turn suggests that no single host group (e.g., bats) can be the natural reservoir, as illustrated through our phylogenetic analysis.

Full Text

Cited Authors

  • Mendenhall, IH; Smith, GJD; Vijaykrishna, D

Published Date

  • July 2015

Published In

Volume / Issue

  • 89 / 14

Start / End Page

  • 6978 - 6981

PubMed ID

  • 25948751

Pubmed Central ID

  • 25948751

Electronic International Standard Serial Number (EISSN)

  • 1098-5514

International Standard Serial Number (ISSN)

  • 0022-538X

Digital Object Identifier (DOI)

  • 10.1128/JVI.02971-14


  • eng