Site of Tc-99m binding to the red blood cell: concise communication.

Journal Article (Journal Article)

The increasing interest in the use of Tc-99m-labeled red blood cells encourages exploration into the site and mechanism of binding of Tc-99m to the RBC components. The components isolated from the labeled red cells were the lipid and protein of the membrane, heme, and the alpha and beta chains of the globin. The binding occurs mainly to the protein moiety, and preferentially to the beta chain of the globin, where the specific activity was found to be 28 +/- 6 times that of the alpha chain. The mechanism of binding is discussed. The role of heme in the binding is not clear.

Full Text

Duke Authors

Cited Authors

  • Rehani, MM; Sharma, SK

Published Date

  • July 1, 1980

Published In

Volume / Issue

  • 21 / 7

Start / End Page

  • 676 - 678

PubMed ID

  • 7391843

International Standard Serial Number (ISSN)

  • 0161-5505


  • eng

Conference Location

  • United States