Site of Tc-99m binding to the red blood cell: concise communication.
Publication
, Journal Article
Rehani, MM; Sharma, SK
Published in: J Nucl Med
July 1980
The increasing interest in the use of Tc-99m-labeled red blood cells encourages exploration into the site and mechanism of binding of Tc-99m to the RBC components. The components isolated from the labeled red cells were the lipid and protein of the membrane, heme, and the alpha and beta chains of the globin. The binding occurs mainly to the protein moiety, and preferentially to the beta chain of the globin, where the specific activity was found to be 28 +/- 6 times that of the alpha chain. The mechanism of binding is discussed. The role of heme in the binding is not clear.
Duke Scholars
Published In
J Nucl Med
ISSN
0161-5505
Publication Date
July 1980
Volume
21
Issue
7
Start / End Page
676 / 678
Location
United States
Related Subject Headings
- Technetium
- Nuclear Medicine & Medical Imaging
- Isotope Labeling
- In Vitro Techniques
- Humans
- Erythrocytes
- Binding Sites
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Rehani, M. M., & Sharma, S. K. (1980). Site of Tc-99m binding to the red blood cell: concise communication. J Nucl Med, 21(7), 676–678.
Rehani, M. M., and S. K. Sharma. “Site of Tc-99m binding to the red blood cell: concise communication.” J Nucl Med 21, no. 7 (July 1980): 676–78.
Rehani MM, Sharma SK. Site of Tc-99m binding to the red blood cell: concise communication. J Nucl Med. 1980 Jul;21(7):676–8.
Rehani, M. M., and S. K. Sharma. “Site of Tc-99m binding to the red blood cell: concise communication.” J Nucl Med, vol. 21, no. 7, July 1980, pp. 676–78.
Rehani MM, Sharma SK. Site of Tc-99m binding to the red blood cell: concise communication. J Nucl Med. 1980 Jul;21(7):676–678.
Published In
J Nucl Med
ISSN
0161-5505
Publication Date
July 1980
Volume
21
Issue
7
Start / End Page
676 / 678
Location
United States
Related Subject Headings
- Technetium
- Nuclear Medicine & Medical Imaging
- Isotope Labeling
- In Vitro Techniques
- Humans
- Erythrocytes
- Binding Sites
- 1103 Clinical Sciences