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Carotid body size on CTA: correlation with comorbidities.

Publication ,  Journal Article
Cramer, JA; Wiggins, RH; Fudim, M; Engelman, ZJ; Sobotka, PA; Shah, LM
Published in: Clin Radiol
January 2014

AIM: To test the hypothesis that computed tomographic angiography (CTA) can identify carotid body enlargement in patients with sympathetically mediated diseases. MATERIALS AND METHODS: A retrospective chart review of all patients obtaining CTAs of the cervical vasculature at University of Utah Health Sciences Center over a 6-month period was performed. Widest axial measurements of both carotid bodies were performed on a picture archiving and communication system (PACS). Statistical analysis was then performed to compare the mean carotid body size between control patients and patients with diabetes mellitus, hypertension, and congestive heart failure. RESULTS: Measurements were performed on 288 patients, with 134 controls. Of the remaining 154, 72 patients had diabetes mellitus, 46 had congestive heart failure, and 130 had hypertension. The control patients had a mean carotid body diameter of 2.3 mm. There was a statistically significant (p < 0.01) 20-25% increase in mean diameter with diabetes mellitus (2.8 mm), hypertension (2.7 mm), and congestive heart failure (2.7 mm; p < 0.01). CONCLUSIONS: This study found a 20-25% larger mean carotid body size in patients with diabetes mellitus, hypertension, and congestive heart failure relative to controls. However, this small enlargement should not mimic other carotid body diseases, such as a paraganglionoma. Moreover, these findings further support the proposed functional relationship between the carotid body and sympathetically mediated disease states.

Duke Scholars

Published In

Clin Radiol

DOI

EISSN

1365-229X

Publication Date

January 2014

Volume

69

Issue

1

Start / End Page

e33 / e36

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Iopamidol
  • Humans
  • Female
  • Contrast Media
  • Comorbidity
 

Citation

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Chicago
ICMJE
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Cramer, J. A., Wiggins, R. H., Fudim, M., Engelman, Z. J., Sobotka, P. A., & Shah, L. M. (2014). Carotid body size on CTA: correlation with comorbidities. Clin Radiol, 69(1), e33–e36. https://doi.org/10.1016/j.crad.2013.08.016
Cramer, J. A., R. H. Wiggins, M. Fudim, Z. J. Engelman, P. A. Sobotka, and L. M. Shah. “Carotid body size on CTA: correlation with comorbidities.Clin Radiol 69, no. 1 (January 2014): e33–36. https://doi.org/10.1016/j.crad.2013.08.016.
Cramer JA, Wiggins RH, Fudim M, Engelman ZJ, Sobotka PA, Shah LM. Carotid body size on CTA: correlation with comorbidities. Clin Radiol. 2014 Jan;69(1):e33–6.
Cramer, J. A., et al. “Carotid body size on CTA: correlation with comorbidities.Clin Radiol, vol. 69, no. 1, Jan. 2014, pp. e33–36. Pubmed, doi:10.1016/j.crad.2013.08.016.
Cramer JA, Wiggins RH, Fudim M, Engelman ZJ, Sobotka PA, Shah LM. Carotid body size on CTA: correlation with comorbidities. Clin Radiol. 2014 Jan;69(1):e33–e36.
Journal cover image

Published In

Clin Radiol

DOI

EISSN

1365-229X

Publication Date

January 2014

Volume

69

Issue

1

Start / End Page

e33 / e36

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Iopamidol
  • Humans
  • Female
  • Contrast Media
  • Comorbidity