Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities


Journal Article

Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich. Systematic phytochemical investigation on heat-processed Epimedium koreanum led to the isolation of 13 flavonoids, including five new prenyl-flavonol glycosides, koreanosides A-E (1-5, resp.). Their structures were elucidated on the basis of detailed analysis of the 1D- and 2D-NMR spectroscopic data and chemical reactions. Apigenin (11) exhibited moderate anti-HIV-1 activity with an EC50 value of 12.8±3.27 μg/ml.

Full Text

Duke Authors

Cited Authors

  • Li, HM; Zhou, C; Chen, CH; Li, RT; Lee, KH

Published Date

  • August 1, 2015

Published In

Volume / Issue

  • 98 / 8

Start / End Page

  • 1177 - 1187

Electronic International Standard Serial Number (EISSN)

  • 1522-2675

International Standard Serial Number (ISSN)

  • 0018-019X

Digital Object Identifier (DOI)

  • 10.1002/hlca.201500123

Citation Source

  • Scopus