Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities
Published
Journal Article
Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich. Systematic phytochemical investigation on heat-processed Epimedium koreanum led to the isolation of 13 flavonoids, including five new prenyl-flavonol glycosides, koreanosides A-E (1-5, resp.). Their structures were elucidated on the basis of detailed analysis of the 1D- and 2D-NMR spectroscopic data and chemical reactions. Apigenin (11) exhibited moderate anti-HIV-1 activity with an EC50 value of 12.8±3.27 μg/ml.
Full Text
Duke Authors
Cited Authors
- Li, HM; Zhou, C; Chen, CH; Li, RT; Lee, KH
Published Date
- August 1, 2015
Published In
Volume / Issue
- 98 / 8
Start / End Page
- 1177 - 1187
Electronic International Standard Serial Number (EISSN)
- 1522-2675
International Standard Serial Number (ISSN)
- 0018-019X
Digital Object Identifier (DOI)
- 10.1002/hlca.201500123
Citation Source
- Scopus