Skip to main content
Journal cover image

Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities

Publication ,  Journal Article
Li, HM; Zhou, C; Chen, CH; Li, RT; Lee, KH
Published in: Helvetica Chimica Acta
August 1, 2015

Systematic phytochemical investigation on heat-processed Epimedium koreanum led to the isolation of 13 flavonoids, including five new prenyl-flavonol glycosides, koreanosides A-E (1-5, resp.). Their structures were elucidated on the basis of detailed analysis of the 1D- and 2D-NMR spectroscopic data and chemical reactions. Apigenin (11) exhibited moderate anti-HIV-1 activity with an EC50 value of 12.8±3.27 μg/ml.

Duke Scholars

Published In

Helvetica Chimica Acta

DOI

EISSN

1522-2675

ISSN

0018-019X

Publication Date

August 1, 2015

Volume

98

Issue

8

Start / End Page

1177 / 1187

Related Subject Headings

  • General Chemistry
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Li, H. M., Zhou, C., Chen, C. H., Li, R. T., & Lee, K. H. (2015). Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities. Helvetica Chimica Acta, 98(8), 1177–1187. https://doi.org/10.1002/hlca.201500123
Li, H. M., C. Zhou, C. H. Chen, R. T. Li, and K. H. Lee. “Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities.” Helvetica Chimica Acta 98, no. 8 (August 1, 2015): 1177–87. https://doi.org/10.1002/hlca.201500123.
Li HM, Zhou C, Chen CH, Li RT, Lee KH. Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities. Helvetica Chimica Acta. 2015 Aug 1;98(8):1177–87.
Li, H. M., et al. “Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities.” Helvetica Chimica Acta, vol. 98, no. 8, Aug. 2015, pp. 1177–87. Scopus, doi:10.1002/hlca.201500123.
Li HM, Zhou C, Chen CH, Li RT, Lee KH. Flavonoids isolated from heat-processed Epimedium koreanum and their anti-HIV-1 activities. Helvetica Chimica Acta. 2015 Aug 1;98(8):1177–1187.
Journal cover image

Published In

Helvetica Chimica Acta

DOI

EISSN

1522-2675

ISSN

0018-019X

Publication Date

August 1, 2015

Volume

98

Issue

8

Start / End Page

1177 / 1187

Related Subject Headings

  • General Chemistry
  • 34 Chemical sciences
  • 03 Chemical Sciences