Persistent and Prolonged Parvovirus B19 Viremia in a Pediatric Patient With Acute Lymphoblastic Leukemia.

Journal Article (Journal Article)

Parvovirus B19 is a small single-stranded DNA virus of the Parvoviridae family. Depending on host factors, it may produce a wide array of clinical disease states. Disease severity can range from self-limited to severe, requiring significant supportive care. Immunocompromised patients are generally affected more severely but rarely develop prolonged and persistent infections. Here, we describe a patient who was diagnosed with parvovirus during maintenance therapy for acute lymphoblastic leukemia and required therapy with intravenous immunoglobulin; the patient remained parvovirus positive according to a polymerase chain reaction testing but had no clinical symptoms for 27 months off chemotherapy.

Full Text

Duke Authors

Cited Authors

  • Fritch Lilla, SA; Burgett, SE; McGann, KA; Wechsler, DS

Published Date

  • September 2015

Published In

Volume / Issue

  • 4 / 3

Start / End Page

  • e38 - e40

PubMed ID

  • 26407441

Electronic International Standard Serial Number (EISSN)

  • 2048-7207

Digital Object Identifier (DOI)

  • 10.1093/jpids/piu112


  • eng

Conference Location

  • England