Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report.

Journal Article (Journal Article)

Navigation with fluorescence guidance has emerged in the last decade as a promising strategy to improve the efficacy of oncologic surgery. To achieve routine clinical use, the onus is on the surgical community to objectively assess the value of this technique. This assessment may facilitate both Food and Drug Administration approval of new optical imaging agents and reimbursement for the imaging procedures. It is critical to characterize fluorescence-guided procedural benefits over existing practices and to elucidate both the costs and the safety risks. This report is the result of a meeting of the International Society of Image Guided Surgery ( on February 6, 2015, in Miami, Florida, and reflects a consensus of the participants' opinions. Our objective was to critically evaluate the imaging platform technology and optical imaging agents and to make recommendations for successful clinical trial development of this highly promising approach in oncologic surgery.

Full Text

Duke Authors

Cited Authors

  • Rosenthal, EL; Warram, JM; de Boer, E; Basilion, JP; Biel, MA; Bogyo, M; Bouvet, M; Brigman, BE; Colson, YL; DeMeester, SR; Gurtner, GC; Ishizawa, T; Jacobs, PM; Keereweer, S; Liao, JC; Nguyen, QT; Olson, JM; Paulsen, KD; Rieves, D; Sumer, BD; Tweedle, MF; Vahrmeijer, AL; Weichert, JP; Wilson, BC; Zenn, MR; Zinn, KR; van Dam, GM

Published Date

  • January 2016

Published In

Volume / Issue

  • 57 / 1

Start / End Page

  • 144 - 150

PubMed ID

  • 26449839

Pubmed Central ID

  • PMC4772735

Electronic International Standard Serial Number (EISSN)

  • 1535-5667

Digital Object Identifier (DOI)

  • 10.2967/jnumed.115.158915


  • eng

Conference Location

  • United States