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Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore.

Publication ,  Journal Article
Chen, PY; Finkelstein, EA; Ng, MJ; Yap, F; Yeo, GSH; Rajadurai, VS; Chong, YS; Gluckman, PD; Saw, SM; Kwek, KYC; Tan, KH
Published in: Asia Pac J Public Health
January 2016

The objective of this study was to conduct an incremental cost-effectiveness analysis from the payer's perspective in Singapore of 3 gestational diabetes mellitus screening strategies: universal, targeted, or no screening. A decision tree model assessed the primary outcome: incremental cost per quality-adjusted life year (QALY) gained. Probabilities, costs, and utilities were derived from the literature, the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study, and the KK Women's and Children's Hospital's database. Relative to targeted screening using risk factors, universal screening generates an incremental cost-effectiveness ratio (ICER) of $USD10,630/QALY gained. Sensitivity analyses show that disease prevalence rates and intervention effectiveness of glycemic management have the biggest impacts on the ICERs. Based on the model and best available data, universal screening is a cost-effective approach for reducing the complications of gestational diabetes mellitus in Singapore as compared with the targeted screening approach or no screening.

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Published In

Asia Pac J Public Health

DOI

EISSN

1941-2479

Publication Date

January 2016

Volume

28

Issue

1

Start / End Page

15 / 25

Location

China

Related Subject Headings

  • Singapore
  • Quality-Adjusted Life Years
  • Public Health
  • Pregnancy
  • Models, Economic
  • Mass Screening
  • Humans
  • Female
  • Diabetes, Gestational
  • Cost-Benefit Analysis
 

Citation

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ICMJE
MLA
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Chen, P. Y., Finkelstein, E. A., Ng, M. J., Yap, F., Yeo, G. S. H., Rajadurai, V. S., … Tan, K. H. (2016). Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore. Asia Pac J Public Health, 28(1), 15–25. https://doi.org/10.1177/1010539515612908
Chen, Pin Yu, Eric A. Finkelstein, Mor Jack Ng, Fabian Yap, George S. H. Yeo, Victor Samuel Rajadurai, Yap Seng Chong, et al. “Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore.Asia Pac J Public Health 28, no. 1 (January 2016): 15–25. https://doi.org/10.1177/1010539515612908.
Chen PY, Finkelstein EA, Ng MJ, Yap F, Yeo GSH, Rajadurai VS, et al. Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore. Asia Pac J Public Health. 2016 Jan;28(1):15–25.
Chen, Pin Yu, et al. “Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore.Asia Pac J Public Health, vol. 28, no. 1, Jan. 2016, pp. 15–25. Pubmed, doi:10.1177/1010539515612908.
Chen PY, Finkelstein EA, Ng MJ, Yap F, Yeo GSH, Rajadurai VS, Chong YS, Gluckman PD, Saw SM, Kwek KYC, Tan KH. Incremental Cost-Effectiveness Analysis of Gestational Diabetes Mellitus Screening Strategies in Singapore. Asia Pac J Public Health. 2016 Jan;28(1):15–25.
Journal cover image

Published In

Asia Pac J Public Health

DOI

EISSN

1941-2479

Publication Date

January 2016

Volume

28

Issue

1

Start / End Page

15 / 25

Location

China

Related Subject Headings

  • Singapore
  • Quality-Adjusted Life Years
  • Public Health
  • Pregnancy
  • Models, Economic
  • Mass Screening
  • Humans
  • Female
  • Diabetes, Gestational
  • Cost-Benefit Analysis