Cartilage repair, replacement, and regenerative strategies for osteochondral lesions of the talus

Book Section

Osteochondral lesions of the talus present a formidable treatment challenge to the orthopaedic surgeon. Historical cartilage repair strategies often result in the formation of fibrocartilage leading to suboptimal clinical results. With advances in regenerative medicine, modern surgical techniques are diverse and employ autograft, allograft, and tissue-engineered constructs for cartilage repair. Fresh and particulated juvenile allograft transplantation have become popular options in the United States. Wordwide, both cellular and acellular tissue-engineered constructs are utilized. In all cases, there is still debate as to the optimal cell source and scaffold material and only short-term clinical results are available. This chapter will review these current as well as experimental techniques for cartilage repair of osteochondral lesions of the talus.

Full Text

Duke Authors

Cited Authors

  • Adams, SB; Parekh, SG; De Solminihac, DHZ; Krynetskiy, EE; Schon, LC; Easley, ME

Published Date

  • June 1, 2014

Volume / Issue

  • 9781447153856 /

Book Title

  • Developing Insights in Cartilage Repair

Start / End Page

  • 269 - 293

International Standard Book Number 10 (ISBN-10)

  • 1447153847

International Standard Book Number 13 (ISBN-13)

  • 9781447153849

Digital Object Identifier (DOI)

  • 10.1007/978-1-4471-5385-6_16

Citation Source

  • Scopus