Information without Implementation: A Practical Example for Developing a Best Practice Education Control Group.

Journal Article (Journal Article)

This article considers methodology for developing an education-only control group and proposes a simple approach to designing rigorous and well-accepted control groups. This approach is demonstrated in a large randomized trial. The Lifestyles trial (n = 367) compared three group interventions: (a) cognitive-behavioral treatment (CBT) for osteoarthritis pain, (b) CBT for osteoarthritis pain and insomnia, and (c) education-only control (EOC). EOC emulated the interventions excluding hypothesized treatment components and controlling for nonspecific treatment effects. Results showed this approach resulted in a control group that was highly credible and acceptable to patients. This approach can be an effective and practical guide for developing high-quality control groups in trials of behavioral interventions.

Full Text

Duke Authors

Cited Authors

  • Balderson, BH; McCurry, SM; Vitiello, MV; Shortreed, SM; Rybarczyk, BD; Keefe, FJ; Korff, MV

Published Date

  • September 2016

Published In

Volume / Issue

  • 14 / 5

Start / End Page

  • 514 - 527

PubMed ID

  • 26485203

Pubmed Central ID

  • PMC4838558

Electronic International Standard Serial Number (EISSN)

  • 1540-2010

Digital Object Identifier (DOI)

  • 10.1080/15402002.2015.1036271


  • eng

Conference Location

  • England