Moderate consumption of white and fortified wine is associated with reduced odds of diabetic retinopathy.

Journal Article (Journal Article)

AIM: To explore the association between alcohol consumption and the severity of diabetic retinopathy (DR). METHODS: In this cross-sectional study, patients with type 2 diabetes answered questions on consumption of low and full-strength beer, white wine/champagne, red wine, fortified wines, and spirits. Never, moderate and high consumption of each alcoholic beverage, and overall alcoholic beverage consumption, were defined as <1, 1-14 and >14 standard drinks/week, respectively. DR was categorized into none; non vision-threatening DR (VTDR) and VTDR. Multivariable logistic regression determined the associations between alcohol consumption and DR. RESULTS: Of the 395 participants (mean age±SD [standard deviation] 65.9±10.4years; males=253), 188 (47.6%) consumed alcohol and 235 (59.5%) had any DR. Compared to no alcohol consumption, moderate alcohol consumption (overall) was significantly associated with reduced odds of any DR (OR=0.47, 95% CI [confidence interval] 0.26-0.85). Moderate consumption of white wine/champagne or fortified wine was also associated with reduced odds of any DR (OR=0.48, 95% CI 0.25-0.91, and OR=0.15, 95% CI 0.04-0.62, respectively). Similar results were observed for non-VTDR and VTDR. CONCLUSIONS: The amount and type of alcohol are associated with risk of DR in patients with type 2 diabetes. A longitudinal study is needed to assess the protective effect of alcohol consumption and DR.

Full Text

Duke Authors

Cited Authors

  • Fenwick, EK; Xie, J; Man, REK; Lim, LL; Flood, VM; Finger, RP; Wong, TY; Lamoureux, EL

Published Date

  • November 2015

Published In

Volume / Issue

  • 29 / 8

Start / End Page

  • 1009 - 1014

PubMed ID

  • 26431588

Electronic International Standard Serial Number (EISSN)

  • 1873-460X

Digital Object Identifier (DOI)

  • 10.1016/j.jdiacomp.2015.09.001


  • eng

Conference Location

  • United States