Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines.

Journal Article (Journal Article)

The NCCN Guidelines for Central Nervous System Cancers provide multidisciplinary recommendations for the clinical management of patients with cancers of the central nervous system. These NCCN Guidelines Insights highlight recent updates regarding the management of metastatic brain tumors using radiation therapy. Use of stereotactic radiosurgery (SRS) is no longer limited to patients with 3 or fewer lesions, because data suggest that total disease burden, rather than number of lesions, is predictive of survival benefits associated with the technique. SRS is increasingly becoming an integral part of management of patients with controlled, low-volume brain metastases.

Full Text

Duke Authors

Cited Authors

  • Nabors, LB; Portnow, J; Ammirati, M; Brem, H; Brown, P; Butowski, N; Chamberlain, MC; DeAngelis, LM; Fenstermaker, RA; Friedman, A; Gilbert, MR; Hattangadi-Gluth, J; Hesser, D; Holdhoff, M; Junck, L; Lawson, R; Loeffler, JS; Moots, PL; Mrugala, MM; Newton, HB; Raizer, JJ; Recht, L; Shonka, N; Shrieve, DC; Sills, AK; Swinnen, LJ; Tran, D; Tran, N; Vrionis, FD; Wen, PY; McMillian, NR; Ho, M

Published Date

  • November 2014

Published In

Volume / Issue

  • 12 / 11

Start / End Page

  • 1517 - 1523

PubMed ID

  • 25361798

Pubmed Central ID

  • PMC4337873

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2014.0151


  • eng

Conference Location

  • United States