A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency.
Publication
, Journal Article
Celmeli, F; Turkkahraman, D; Uygun, V; la Marca, G; Hershfield, M; Yesilipek, A
Published in: Pediatr Transplant
March 2015
PNP deficiency is a rare combined immunodeficiency with autosomal recessive mode of inheritance. The immunodeficiency is progressive with normal immune functions at birth, but then, T-cell deficiency with variable B-cell functions usually presents by the age of two yr. The only curative treatment for PNP deficiency is hematopoietic stem cell transplantation. Here, we present a 13-yr-old girl with late-onset PNP deficiency. Despite many complications of infections, she was successfully transplanted with a reduced intensity-conditioning regimen from an HLA-identical unrelated donor.
Duke Scholars
Published In
Pediatr Transplant
DOI
EISSN
1399-3046
Publication Date
March 2015
Volume
19
Issue
2
Start / End Page
E47 / E50
Location
Denmark
Related Subject Headings
- Transplantation Conditioning
- Surgery
- Respiratory Tract Infections
- Receptors, Antigen, T-Cell
- Purine-Pyrimidine Metabolism, Inborn Errors
- Purine-Nucleoside Phosphorylase
- Primary Immunodeficiency Diseases
- Peripheral Blood Stem Cell Transplantation
- Paraplegia
- Mutation
Citation
APA
Chicago
ICMJE
MLA
NLM
Celmeli, F., Turkkahraman, D., Uygun, V., la Marca, G., Hershfield, M., & Yesilipek, A. (2015). A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency. Pediatr Transplant, 19(2), E47–E50. https://doi.org/10.1111/petr.12413
Celmeli, Fatih, Doga Turkkahraman, Vedat Uygun, Giancarlo la Marca, Michael Hershfield, and Akif Yesilipek. “A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency.” Pediatr Transplant 19, no. 2 (March 2015): E47–50. https://doi.org/10.1111/petr.12413.
Celmeli F, Turkkahraman D, Uygun V, la Marca G, Hershfield M, Yesilipek A. A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency. Pediatr Transplant. 2015 Mar;19(2):E47–50.
Celmeli, Fatih, et al. “A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency.” Pediatr Transplant, vol. 19, no. 2, Mar. 2015, pp. E47–50. Pubmed, doi:10.1111/petr.12413.
Celmeli F, Turkkahraman D, Uygun V, la Marca G, Hershfield M, Yesilipek A. A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency. Pediatr Transplant. 2015 Mar;19(2):E47–E50.
Published In
Pediatr Transplant
DOI
EISSN
1399-3046
Publication Date
March 2015
Volume
19
Issue
2
Start / End Page
E47 / E50
Location
Denmark
Related Subject Headings
- Transplantation Conditioning
- Surgery
- Respiratory Tract Infections
- Receptors, Antigen, T-Cell
- Purine-Pyrimidine Metabolism, Inborn Errors
- Purine-Nucleoside Phosphorylase
- Primary Immunodeficiency Diseases
- Peripheral Blood Stem Cell Transplantation
- Paraplegia
- Mutation